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The largest trial involving DSIP to date, which included a total of 107 volunteers, reported that the peptide was generally well-tolerated with mostly minor side effects, which included [8]: Low blood pressure Increased sweating Headache Nausea Vertigo Considering that the drop in blood pressure was reported as moderate to severe in some patients, researchers should consider hypotension as a potentially exclusionary criterion for DSIP research

In this trial, 203 obese individuals were divided into four groups: placebo, 0.25 mg, 0.5 mg, and 1 mg Tesofensine daily

Numerous case studies report of severe impediments to the childs development as a result of B12 deficiency in the mother (48-50)

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