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When compared to control iPSCs, neurons from FRDA iPSCs demonstrated a reduced mitochondrial membrane potential and a delayed development of electrophysiological functionality following differentiation, confirming a role of mitochondrial pathogenesis in FRDA and providing several cellular phenotypes for further study [10]

During a physical exam, a health care provider usually examines a patients body, which can include checking for discharge from the urethra enlarged or tender lymph nodes in the groin a swollen or tender scrotum performs a digital rectal exam A digital rectal exam, or rectal exam, is a physical exam of the prostate

At the organ level, MFs can influence larger brain networks, which play a critical role in coordinating functions such as motor control, cognition, and emotion (Lu et al., 2024

Meng Q, Chen C, Yang N, Gololobova O, Shi C, Dunn CA, et al