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A randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans

Investigative potential in: Cellular signaling pathway mapping related to structural integrity and recovery

The dominant signaling pathway is the activation of VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) with downstream Akt-eNOS phosphorylation , leading to rapid release of nitric oxide and the formation of new capillaries 3

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