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Simuni T, Chahine LM, Poston K, Brumm M, Buracchio T, Campbell M, et al

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Once cisplatin reacts with DNA, the cell must clear or tolerate the lesions to survive

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It helps the intestinal endothelium and promotes enterocyte proliferation, regulates tight junction proteins, suppresses proinflammatory signaling pathways, and confers protection against apoptosis and cellular stresses during normal and pathological conditions (Perna et al., 2018)

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The liver injury pattern helps guide further testing such as ruling out primary biliary cholangitis or sclerosing cholangitis in cases of cholestasis or evaluating for biliary tract obstructions if jaundice is present [59]

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