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methionine cycle enzymes are enriched in many tumor types

Given that these chiral modifications are driven by distinct chiral metabolites in cells and they may be regulated by enzymes in different ways, as well as recognized by diverse recognition proteins (or readers), the ability to differentiate between stereoisomers of PTMs holds significant importance 36

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Obviously, following KU-57788 treatment, mitochondria in both 8505C and Hth-7 cells became irregular, with smaller spherical or short rod-like shapes, whereas mitochondria predominantly exhibited elongated or oval shapes in the control group (Fig