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Mohamed 1 , Hussien Osama 1 , Muataz Kashbour 2 , Ahmed Amin 3 1 Faculty of medicine, Mansoura University, Mansoura, Egypt, Mansoura, Egypt, 2 Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya, Misrata, Libya, 3 Faculty of Medicine, Al-Azhar University, Cairo, Egypt, Cairo, Egypt Background and Aims: Cerebral edema is a serious complication of ischemic and hemorrhagic strokes, contributing to increased mortality and poor clinical outcomes

In very rare cases, people who are sensitive or allergic to cobalt may experience skin reactions, especially after high-dose B12 injections

Some also report mild localised redness, small lumps, or temporary irritation