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Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, Han L, Han K, DiGregorio GB, Katzenellenbogen JA, Katzenellenbogen BS, Roberson PK, Weinstein RS, Jilka RL, Manolagas SC

In those cancers relying on lipid metabolism, CD36 and other fatty acid binding proteins (FABP) are over-expressed to catch fatty acids stored in surrounding adipocytes (Koundouros and Poulogiannis, 2020)

CaP cells depend strongly on the AR NTDs ligand-independent transactivation domain AF1, which mediates also transcriptional activity of agonist- and antagonist-indifferent AR variants after acquired resistance to ADT, but to date cannot be effectively inhibited in clinic [45]

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