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the invention encompasses a method of providing muscular therapy by administering a cation of Formula I, wherein: R 1 is C 1-4 alkyl R 2 , R 3 , R 4 , and R 5 are independently selected from the group consisting of: H, C1-4 alkyl, halogen-substituted C 1-4 alkyl, NR 9 R 10 , and CN

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63 presented a case, where the patient had a history of recreational use of alcohol and kratom

The degeneration of neurons producing dopamine in the substantia nigra leads to a depletion of dopamine within the striatum, disrupting the finely tuned excitatory and inhibitory signaling in the basal ganglia