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The outer layers of the grain (the bran and the aleurone layer, the outermost layer of the endosperm, remaining attached to the bran during milling) and the germ are rich in folate, and they are generally separated during milling from the starchy endosperm, which is ground into flour 304,305,306,307,308,309,310,311,312,313,314,315,316,317,318

Recently, there has also been a large number of reports indicating that statins inhibit the expansion and metastasis of cancer via the Hippo pathway

doi: 10.1152/ajpheart.00535.2010 198 MaSWangJLinJJinSHeFMeiJet al