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While this can be beneficial for drugs with low bioavailability or metabolic stability, this pharmacokinetic alteration can have a negative impact on drugs with an extremely narrow therapeutic index, such as captopril, lisinopril, and digoxin ( 14 The strengths and the weakness The present study includes both in vivo and in vitro experimental and clinical trials, which can provide a comprehensive overview of the mechanism and function of the most essential and promising flavonoids, resulting in a potential perspective for future researchers

Recent studies have highlighted that CD8 + T cells exhibit selective depletion in the duodenum of patients with ALD, resulting in compromised intestinal barrier function and exacerbation of ALD pathology

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10.1186/s12872-024-04232-z 62 YanX.WangX.ZhangJ.MingZ.ZhangC.MaP.et al (2024)