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In conclusion, catalase, in the context of cancer, reflects the dual functions of ROS, acting as both a tumor suppressor and a prosurvival protein

Am Fam Physician 72:12771282 [PubMed] [Google Scholar] Guindo A, Fairhurst RM, Doumbo OK, Wellems TE, Diallo DA (2007) X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria

Biochem Biophys Res Commun 176(2):887893 Temmerman L, Slonimsky E, Rosenthal N (2010) Class 2 IGF-1 isoforms are dispensable for viability, growth and maintenance of IGF-1 serum levels

Only 18 percent of the 69 subjects in the low glutathione group survived