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The dermoscopic finding of prominent skin markings was recently described as a powerful diagnostic indicator of melanoma in situ versus atypical nevus, particularly in sun-damaged areas of the skin.1 These markings, which are associated with high levels of interobserver agreement, are intersecting linear furrows, lighter in color than the rest of the lesion

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Annu Rev Biochem (1994) 63(1):17595

However, on day 15, one patient experienced a serious complicationretinal detachment with proliferative vitreoretinopathynecessitating their removal from the trial