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Neonatology 2008

Notably, all reported mutations in NFE2L2 were gain-of-function, and 40% in KEAP1 were loss-of-function, suggesting that constitutive antioxidant pathway stimulation is protective against ionizing radiation

industry reporting on the program and trial outcomes is summarized in clinical communications and trade coverage such as the Metabolic Pharmaceuticals trial update: Phase 2b OPTIONS Study coverage