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doi: 10.1016/j.nut.2020.111023 120

Most adults need 2.4 mcg per day, but vegetarians, vegans, masters athletes over 50, and high-volume endurance athletes are at elevated deficiency risk

Loading Phase Option Some protocols recommend 8mg daily for the first two weeks (5 days on, 2 days off), followed by 4mg daily for 10 weeks using the same schedule

This is one of the first studies suggesting that TBK1 mediated S403 phosphorylation regulates autophagosomal engulfment of ubiquitinated mitochondria as an immediate response to the mitochondrial depolarization under neurodegeneration