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8 A growing body of evidence has shown that regeneration and maintenance of the cellular NADP(H) content is strongly implicated in a variety of pathological conditions, such as diabetes, cardiovascular disease, neurodegenerative diseases, aging, 4,5 especially in tumorigenesis and cancer progression

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Strbe et al., 2021), with one or two vessel ligations (Vukojevic et al., 2018

The observed loss of GSG volume, and the corresponding tubular atrophy, may explain the reduction in renal cortical volume associated with aging