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25, 38, 40 BSO+L-PAM was synergistic (CIN 0.30.7) in OPM-2 (t(4;14)(p16;q32)), NCI-H929 (t(4;14)) TX-MM-030h (post-BMT) and MOLP-2 (t(11;14)(q13;q32)) 39 cell lines (Figures 1ac)

Astrogliosis is prevalent in the epilepsies, and interestingly a mouse forebrain neuron-specific knockout of SOD2 resulted in seizures, oxidative stress, and marked GFAP and vimentin gene upregulation, indicative of astrogliosis resulting from increased neuronal mtROS (Mndez-Armenta et al., 2014

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miRNAs miRNAs have demonstrated significant potential as biomarkers for diagnosis, tumor grading, and monitoring treatment response in GBM