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Description

ZhouJLiuMSunHFengYXuLChanAWHet al

Typical starting doses range from 0.5 g to 2 g (10 - 40 mL of the 50 mg/mL solution) given intermittently (e.g., weekly)

(iii) Cultivation conditions : protein production can be efficiently improved by the use of high cell-density culture systems like batch, which offers a limited control of the cell growth, and fed-batch, which allows the real time optimization of growth conditions (Sorensen and Mortensen, 2005b)

The key is regular monitoring via lab work and clinical assessment