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This review highlights the biocatalyst-mediated synthesis of nicotinic-acid- and nitrile-metabolizing enzymes through state-of-the-art omics-based techniques to improve enzyme catalytic efficiency and stability via various approaches

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In the chronic window ( week 3) focus turns to maintenance/remodelling: preventing relapse, limiting fibrosis and endothelial dysfunction and leveraging lifestyle hormesis alongside gentle, compartment-targeted pharmacology