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Abraldes 2 , Mayur Brahmania 3 and Abdel-Aziz Shaheen 3 , (1)University of Calgary, (2)University of Alberta, AB, Canada, (3)Cumming School of Medicine, University of Calgary, Calgary, AB, Canada Background: Alcohol- (AC) and non-alcohol-related cirrhosis (NAC) epidemiology studies are limited by the accuracy of available administrative case definitions

The mucus layer prevents pathogenic bacteria in the intestinal lumen from contacting the intestinal epithelium (McGuckin et al., 2011)

J Dermatolog Treat 33(4):21102117

In osteoarthritic joints, features of the local microenvironment, such as acidic synovial fluid, accumulation of reactive oxygen species, and elevated expression of matrix metalloproteinases and proinflammatory cytokines, accelerate cartilage degeneration and synovitis (Yao et al., 2023)