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Despite some factors and small molecules (compounds) being shown to improve myelination in cell cultures, as well as remyelination in animal models, no medication presenting convincing remyelinating capacity in humans has been approved for MS patients so far, with clemastine and analogs of thyroid hormone still having to complete phase III clinical trials 23,24,25,26

Gregg Roman, Ruofan Cao, and John Adams in the Imaging Research Core of GlyCORE at the University of Mississippi for their assistance with using the Leica SP8 Inverted Confocal Microscope

-Replenishes glutathione and vitamin C stores in the body

K.OhM.-J.WanJ.et al