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10.1016/j.jnutbio.2020.108479 106

Free Radic Biol Med (2019) 133:16268

arachidylglucoside - Arachidyl Glucoside - - , .- , ,

Dihydroartemisinin can induce ferroptosis in PDAC cells, and dihydroartemisinin combined with cisplatin can cause catastrophic accumulation of free iron and mitochondria-derived ROS in PDAC cells and lipid peroxidation, and impaired mitochondrial homeostasis, 187 indicating ferroptosis can increase the cytotoxicity of cisplatin to PDAC cells and overcome PDAC cisplatin resistance