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G.ZhangR.LauK

Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice

This stability profile distinguishes it from many peptide-based research compounds and has contributed to interest in its biochemical persistence, signaling activity, and pathway-specific effects in mechanistic investigations

[5] It proceeds via acid-base catalysis through a three-step mechanism, involving two strictly conserved amino acid residues, a lysine (Lys) and a glutamate (Glu)