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Description

Respiratory Wellness The lungs are constantly exposed to oxygen and environmental pollutants, making them a high-stress environment for cells

Amino Acids 2012 , 736837 (2012)

No history was suggestive if systemic illness

In this context, cells reroute glutamine into the reductive carboxylation pathway: NADP + -dependent isocitrate dehydrogenase runs in reverse to convert -ketoglutarate (from glutamine) into citrate, which is cleaved to acetyl-CoA for fatty acid synthesis 98