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Because a major physiologic function of GSH is to provide cells with a reducing environment and to destroy the reactive oxygen compounds and free radicals formed in metabolism, organs that have low concentrations of other antioxidants (such as catalase and superoxide dismutase) are thought to be more dependent on GSH for detoxification of reactive oxygen species than are organs that have alternative antioxidants

This does not establish a human appetite or weight-loss effect

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Furthermore, it is not known whether man possesses inducible GST and if so, whether these might be involved in AFB 1 metabolism [34]