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Another study showed that the blood-brain barrier that complicates the treatment with chelating agents in the setting of Wilson disease can be successfully passed by vectorized liposomes in which chelating agents such as triethylenetetramine (TETA) can be encapsulated

No participants withdrew from any trial due to tolerability issues, indicating that even when side effects occurred, they were sufficiently manageable that participants chose to continue treatment

Once Nrf2 is activated, the storage of iron would increase, OS would be inhibited, and the occurrence of ferroptosis could be directly blocked

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