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glutathione inhibitor bso

glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model

Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo Journal of Biological Chemistry bso glutathione The synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Buthionine (S Multiomics reveals glutathione metabolism as Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression ScienceDirect Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma ScienceDirect

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DOI: 10.1038/jhh.2008.57 Morton C, Hickey-Dwyer M (1992): Cortical blindness after nifedipine treatment

glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model

Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E, Mittal M, Barit D et al (2010) Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model

Doucette, J

glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model

To develop this report, this PKD Burden of Disease working group had multiple focused online discussions over the course of 1 year and an in-person meeting in San Diego (CA, USA)

glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model
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