glutathione inhibitor bso L-Buthionine-(S,R)-sulfoximine (L-Buthionine sulfoximine) | G-glutamylcysteine Synthetase Development of a mouse model
Development of a mouse model expressing a bifunctional glutathione synthesizing enzyme to study glutathione limitation in vivo Journal of Biological Chemistry bso glutathione The synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Buthionine (S Multiomics reveals glutathione metabolism as Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression ScienceDirect Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma ScienceDirect
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