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IGF1 elevation: Sustained administration can significantly increase IGF1 levels [5]

Taken together, these data demonstrate that cancer cells capable of enduring 5FU treatment have significant, sustained mitochondrial adaptations, driving enhanced mitochondrial biogenesis and fusion in the absence of evident mitochondrial dysfunction

Parasitology (1989) 99:22939.10.1017/S0031182000058686 125 HarnettWHarnettMM

Providers should maintain a high index of suspicion for endometriosis in women with severe dysmenorrhea, particularly when symptoms are progressive or interfere with daily activities