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Similar to WASP, loss of WAVE protein or manipulations of its phosphorylation status by cyclin-dependent kinase 5 (Cdk5) also caused deficits in spine formation and maintenance in mice (Soderling et al., 2003, 2007

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These molecules often adopt distinct secondary and tertiary structures, frequently featuring post-translational modifications that are essential for their biological activity (Xuan et al., 2023

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