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Description

The sequestration of oxidized glutathione and detoxification of H 2 O 2 in vacuoles during oxidative stress may be involved in the control of cytosolic redox potential and redox state of target molecules and subsequently in the regulation of cell division, differentiation, and defense

In vitro studies provide further mechanistic insight, showing that lithium enhances mitochondrial function, supports oxidative balance, and prevents apoptosis through mechanisms involving cytochrome c regulation, Bcl-2 modulation, and preservation of complex I activity

10.1210/edrv.22.1.0417 33 CamposH

Minet A, Manceau A, Valada-Mennuni A, BraultFavrou M, Churlaud C, Fort J, Nguyen TM, Spitz J, Bustamante P, LacoueLabarthe T (2020) Mercury in the tissues of five cephalopods species: first data on the nervous system