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This has contributed to the development and approval of more than 100 peptide-based drugs globally, alongside a growing research pipeline (Musiami, 2024)

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Together, the above studies suggest that macrophage-derived lncRNAs are not independent mediators, but collectively integrate into few physical axes of immunoregulation: macrophage polarization, cytokine and chemokines production, immune checkpoint regulation, and inflammatory programs epigenetic regulations