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Little is known about the factors that could contribute to the instability of the CGG repeats in FMR1

Toluidine blue staining solution (G3660, Solarbio, Beijing, China) was added to the wells and stained for 5 min, and then, equal amount of distilled water was added and mixed, left for 15 min, washed twice with distilled water, and observed under the microscope

Risk increases significantly in individuals with copper metabolism disorders (Wilsons Disease)

Ferroptosis can therefore be induced by depriving cells of the sulfur-containing GSH precursor, cysteine, via inhibition of the system x c cystine/glutamate antiporter (e.g., using small molecules of the erastin family), or by direct inhibition of GPX4 itself (Forcina & Dixon, 2019)