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Mouse model of RMC recapitulates hyperprogressive disease response to ICT treatment To confirm hyperprogression and myeloid mimicry in controlled experimental settings, we performed preclinical experiments in an immunocompetent mouse model of RMC (Fig

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Real-time surface plasmon resonance (SPR) spectroscopy was performed on a BIAcore X100 instrument (GE Healthcare) with HEPES-buffered saline supplemented with Tween (HBST

For intracellular staining, cells were incubated with antibodies against cellular activation markers for 20 min at RT