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2021 Oct 4;11(10):1835

Physical Pharmacy, 4ed., Williams and Wilkins, Baltimore, USA, pp 396398, 1993

In animal studies, target mutation HGF or MET, or both genes caused abnormalities that led to embryonic lethality [42]

In a controlled study by Samsom and colleagues, healthy subjects given pramlintide showed gastric-emptying half-times that lengthened from about 112 minutes on placebo to roughly 169 minutes at 30 g and 177 minutes at 60 g a delay of more than an hour at the higher dose