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Proteins should be kept in a well-buffered environment to prevent sudden changes in pH that could irreversibly affect their folding, solubility, and function

These data suggest that Cinobufagin combined with chemotherapy can improve the clinical efficacy and quality of life of BC patients [35]

doi: 10.1016/0098-2997(93)90002-U, PMID: [DOI] [PubMed] [Google Scholar] 41.Spanos C, Maldonado EM, Fisher CP, Leenutaphong P, Oviedo-Orta E, Windridge D, et al