define glutathione s-transferase transferases as mediators of signaling pathways involved in cell proliferation and cell death Glutathione transferases: substrates, inihibitors and

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It is also poorly understood how mTORC1/2 complexes are targeted to specific subcellular locations and whether there are specific signatures (for example, posttranslational modifications or scaffolding interactions) that maintain them at these sites

Three histidines (His 61, His 69, and His 78) and one aspartic acid residue (Asp 81) coordinate the Zn ion, giving it a warped tetrahedral geometry [45]

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