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Producers of those products should consider either denaturing the FBP or replacing folic acid with 5-methyl-THF as fortificant

Moreover, preconditioning MSC-EVs with traditional Chinese medicine (TCM) components, such as those from Salvia miltiorrhiza, upregulates hsa-miR-27a-5p_R-1 to modulate the signal transducer and activator of transcription 3 (STAT3)-SHANK2 (SH3 and multiple ankyrin repeat domains protein 2) axis, significantly improving the EVs anti-fibrotic and tissue-repair capabilities [194]