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Additionally, the damage of the mitochondrial membranes and protein structure can enhance the generation of ROS and lead to DNA impairment and cell death by apoptosis [27]

In the future, more attention should be paid to the long-term safety and efficacy of targeted drugs in future clinical studies

When co-cultured with activated leukocytes, the alveolar epithelial cells showed only 67% viability, but this increased with the addition of n(CAT) in a dose-dependent manner, from 78% to 91%