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(4) Standard therapy combines atropine, which antagonizes muscarinic receptor overstimulation, with pralidoxime (2-PAM), which reactivates uninhibited or non-aged AChE

Preclinical studies have shown that the subtherapeutic dose of local RT combined with NKG2D-based CAR T cells can promote the migration of CAR-T cells to the tumor site, resulting in a synergistic effect in two independent syngeneic mouse glioma models (101)

Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression