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These results demonstrate that repRNA delivery of gH/gL is a viable strategy to elicit high titers of neutralizing antibodies necessary for protection in humanized mice that obviates the challenges of expressing and purifying gH/gL nanoparticles

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While the evidence is somewhat mixed, a recent review concluded that vitamin B12 supplementation can delay the onset of depression and improve the effectiveness of antidepressants. Supplementing with vitamin B12 appears to be a fairly straightforward approach for trying to improve mood

Thus, among participants without a current diagnosis of MDD we excluded those with a diagnosis of anxiety disorder (n = 508) and dysthymia or minor depression (n = 66)