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The disorder was also found to be associated with a significant increase in cardiovascular mortality (38)

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Most men notice symptomatic improvements within 4 to 6 weeks if the biochemical response is favorable, though the full benefit to muscle recovery, mood, and libido often takes 8 to 12 weeks to consolidate

462 Magnetic resonance perfusion imaging studies have identified increased thalamic vascularity in patients with PDPN during resting states, likely reflecting heightened neuronal activity