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14.1 Consensus statements 14.1.1 Approximately 721% of children with autoimmune hepatitis presents as acute liver failure (LOE 4)

Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclinical studies, clinical trial results have been disappointing

The perfusion solution was then switched to solution B (composed of 67 mM NaCl, 6.7 mM KCl, 10 mM HEPES, 0.5% BSA, 4.8 mM CaCl 2 2H 2 O (all provided by Sigma-Aldrich), and 1 g l 1 collagenase P (Roche) in ddH 2 O (pH 7.6), diluted 1:2 in stop solution (composed of DPBS with Ca 2+ , Mg 2+ (Gibco), supplemented with 16.7% FBS (Merck)) and perfused at 39 C for 515 min at a rate of 25 ml min 1

World Health Organization: WHO & World Health Organization & Dementia (2025)