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Study on the interaction between active components from traditional Chinese medicine and plasma proteins

This was further substantiated by the observation that inhibiting heightened GJ function with a GJ inhibitor in mice effectively diminished APAP toxicity, which correlated with reduced levels of oxidative stress in hepatocytes

Animal experiments All animal procedures were performed in accordance with the ethical standards approved by the Animal Care and Ethics Committee of the Second Affiliated Hospital, Zhejiang University School of Medicine

2, 5, 6), the calculated binding free energy again indicates the rapid oxidation of C3G against EC and CH compounds