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The field of cataract surgery was transformed in 1967 when Charles Kelman introduced the phacoemulsification technique [77], commonly known as "phaco", where the cataractous lens is broken up by an ultrasonic probe, allowing aspiration through a 3-mm incision [78]

The results indicate that the short- and long-term memory impairment is the result of a reduction on neuron cells density pattern in the CA3 and DG of the hippocampus, besides an intense modulation of the hippocampal proteomic profile of proteins related to synaptic function, neuroplasticity and energy metabolism