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This review cited Kurokawa et al.s results that indicated that patients with Hamilton Depression Rating Scale (HAM-D) scores 8 exhibited reduced microbial diversity compared to healthy donors, and that increased microbial diversity following FMT treatment positively correlated with symptom improvement (Zhang et al., 2025)

Individual tolerance, comorbidities, concurrent medications, and biomarker trends must guide any schedule changes

shown that mitochondrial dysfunction increased intracellular H 2 O 2 , Fe 2+ levels and might lead to increased production of -OH, resulting in lipid peroxidation and ferroptosis (Takashi et al., 2020)