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Engineering these vesicles through genetic and biochemical modifications has expanded their therapeutic potential, enabling precise cargo delivery, improved targeting specificity, and enhanced stability

J Immunol 2004

(1998) NFB and Rel proteins: Evolutionarily conserved mediators of immune responses

This hypothesis article discusses this immunometabolic mechanistic cascade in-depth in the context of intensified short-term vaccine side effects, as well as serious inflammatory and neurological sequelae experienced by more vulnerable individuals