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While 95% of creatine in the body is found in skeletal muscle, more recent research has highlighted the important role of the quantity located in the brain

The higher prevalence of both anemia and OWOB in adolescent girls, compared with that in boys, could be explainable by the higher consumption of energy-dense foods (sweets, cakes and donuts, burgers, French fries, and hot dogs), lower consumption of fruits and vegetables 48,49,57,58 , lower consumption of iron rich foods such as animal protein 59 , and lack of physical activity 48

In most cases, the condition is self-limited and responds to supportive care and symptomatic relief including rest, elevation if a dependent extremity is affected, and use of compression stockings

The high expression of the lysyl oxidase-like 2 (LOXL2) gene is closely associated with the high invasiveness of tumors and the metastasis and prognosis of female breast cancer (109, 110)