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10.3390/ijms22010418 92 SawulaW.Banecka-MajkutewiczZ.KadzinskiL.Jakobkiewicz-BaneckaJ.WegrzynG.NykaW.et al (2009)

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Therefore, by activating this NCOA4-mediated ferritinophagy pathway, Erastin promotes the release of free iron, which in turn amplifies ROS production and lipid peroxidation, resulting in an autophagy-dependent mode of ferroptosis