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This article aims to review the research progress on key scientific issues such as the dynamic plasticity of T-cell exhaustion states, the heterogeneity boundary between exhaustion and dysfunction, and microenvironment-driven epigenetic reprogramming

So far, six patients with BP were reported to have received tralokinumab, five of them in combination with oral prednisolone

These extremely low GA infants may not have surfactant deficiency or RDS but instead have early requirements for oxygen and ventilatory support due to multiple factors leading to respiratory instability of prematurity 127,128,129

In a study by Vanderhoof et al., 41 oral erythromycin (20 mg/kg/day) was tried to patients with CVS as a prokinetic agent, which was suggested to be effective in some patients, but the efficacy was not confirmed due to poor quality of the study