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However, their efficacy is linked to the need of a minimum intake of caffeine of 3 mg/kg (Jimnez et al., 2021), considered the optimal dose for the ergogenic effects (Guest et al., 2021)

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lipolytica can utilize hydrophobic substrates (e.g., oleic acid) for growth, ex novo lipid synthesis, and bioproduct synthesis (e.g., citric acid), hence its species nomenclature (Madzak, 2021)

Patient education can include strategies such as pacing, energy conservation, increasing lifestyle physical activity, getting regular exercise, rest-activity balance, balanced diet, lifestyle moderation, stress management, time management, and sleep hygiene