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It will be interesting to investigate whether persistent BCL-2 expression in AR cyto CRPC cells is caused by, in addition to the loss of AR-mediated BCL-2 repression, signaling functions of cytoplasmic AR and/or by other nuclear TFs such as NF-B, STAT33 and E2F1

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Health Quality Ontario makes no representation that the literature search captured every publication that was or could be applicable to the subject matter of the report

Patients with significant acid/base imbalance should have their condition corrected before diuretics, like hydrochlorothiazide